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Cell division and genome organization in development and aging

日期: 2018-09-18
永利官网2018年度秋季学期学术系列讲座之一
题目:Cell division and genome organization in development and aging
讲座人:Yixian Zheng, Ph.D.
Director, the Department of Embryology
Interim co-President, Carnegie Institution for Science
时间:2018年9月18日(星期二),13:00-14:30
地点:我院邓祐才报告厅
主持人:宋艳研究员
摘要:
My lab studies cell division and genome organization in the context of development and aging. My seminar will be two parts. I will first highlight a number of findings we have made that have led us to uncover how protein phase separation is involved in regulating mitotic spindle assembly and cell division. In the second part of my discussion, I will describe how the nuclear lamina protein regulates genome organization, organ building, and aging.
References:
Jiang H, Wang S, Huang Y, He X, Cui H, Zhu X, and Zheng Y (2015). Phase Transitions of Spindle-Associated Protein Regulate Spindle Apparatus Assembly. Cell 163:108-122.
Zheng X, Hu J, Yue S, Kristiani L, Kim M, Kim Y, Zheng Y (2018). Lamins organize the three dimensional genome from nuclear periphery in ES cells. Molecular Cell (In press)

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博士后招聘:/upfile/file/20180909/20180909081750_58422.pdf