永利官网2017年度秋季学期学术系列讲座之八
题目：Structures and mechanisms of macromolecular complexes involved in DNA processing
讲座人：Xiaodong Zhang, Ph.D.
Professor, 
Department of Medicine, 
Imperial College London
时间：2017年11月3日（星期五），13:00-14:30
地点：我院邓祐才报告厅 
主持人：苏晓东
摘要：
Almost all activities inside our cells are carried out by macromolecular complexes. Defects in these protein and complexes can cause malfunction and diseases. My research focuses on elucidating the structures and mechanisms of large macromolecular complexes, especially those involved in DNA processing, such as transcription regulation and DNA damage response, by combining biochemistry, X-ray crystallography and electron microscopy techniques. I will discuss our work on understanding the mechanisms of transcription regulation, especially how the initial DNA opening occurs during transcription initiation. I will also discuss our recent progress on elucidating structures and mechanisms of protein complexes involved in chromatin remodelling, DNA damage signalling and repair. 
欢迎各位老师同学积极参加！